Research & Publications
A selection of studies, neuroscientific research, and medical journal articles featuring contributions from Dr. Ayesha Sherzai and Dr. Dean Sherzai.
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A Systematic Review of Omega-3 Fatty Acid Consumption and Cognitive Outcomes in Neurodevelopment
A systematic review addressing the effects of n-3 long-chain polyunsaturated fatty acids consumption on human neurodevelopment, evaluating articles published between 2000 and 2022, investigating the cognitive outcomes during the period of neurodevelopment: from fetal development to adolescence.
A Systematic Review of Omega-3 Consumption and Neuroprotective Cognitive Outcomes
This systematic review assesses the cognitive effects of n-3 long-chain polyunsaturated fatty acids (LC PUFAs) across the lifespan, accounting for population differences and highlighting methodological limitations of extant studies.
The INFINITE Study: Pilot Research Exploring Plant-Based Nutrition in Treatment for Substance Use Disorders
Standard treatment for substance use disorders (SUDs) rarely incorporates a dietary intervention. The purpose of this research is to explore how nutrition might influence early recovery outcomes, with a particular focus on whole food plant-based nutrition.
Lifestyle Intervention and Alzheimer’s Disease
In this article, we look at the ways lifestyle intervention can play a key role in substantially lowering the risk of developing Alzheimer’s disease (AD), the most prevalent type of dementia, which represents the fastest-growing epidemic both in the United States and globally.
Retinal Venular Tortuosity Jointly with Retinal Amyloid Burden Correlates with Verbal Memory Loss: A Pilot Study
In this exploratory retinal curcumin-fluorescence imaging (RFI) study, we sought to determine whether retinal vascular features combined with retinal amyloid burden correlate with the neurocognitive status.
Gut dysbiosis, insulin resistance, and Alzheimer’s disease: review of a novel approach to neurodegeneration
This review elaborates the role that cerebral insulin resistance (IR) might play in the underlying pathological events in the development of Alzheimer’s disease (AD).
Sectoral segmentation of retinal amyloid imaging in subjects with cognitive decline
We used the specific amyloid-binding fluorophore curcumin and laser ophthalmoscopy to assess retinal amyloid imaging (RAI) in 34 patients with cognitive decline to assess whether quantitative RAI is a feasible technique for predicting hippocampal volume.
Studies have demonstrated an inverse relationship between Alzheimer’s disease (AD) and cancer. This inverse relationship was further explored in this inpatient sample analysis. In addition, Pin1 expression has been implicated in the cell cycle regulation of both disease processes.
Dementia is the fastest-growing epidemic in the developed nations. This article reviews the five lifestyle factors of the ‘NEURO’ acronym we created — N for Nutrition, E for Exercise, U for Unwind, R for Restorative Sleep, and O for Optimizing Mental and Social Activity — and their roles in preventative lifestyle.
Strong Association Between Migraine and Transient Global Amnesia: A National Inpatient Sample Analysis
The purpose of this article was to explore sex- and race-specific variables and comorbidities associated with transient global amnesia (TGA) using a nationally representative database.