Ozempic. Developed as diabetes medication. Adopted as a weight loss drug. Eyed for its potential neuroprotective effects.

Hollywood’s popularization of Ozempic as a way to lose weight has made it one of the most widely-discussed drugs of our time, and has put immense stress on supply chains, sometimes preventing its intended users — type-2 diabetics — from accessing the medication.

In this episode, we wade through the history, benefits, side-effects, neuroscience, and future of Ozempic, with the help of our guest: obesity and lipid physician Dr. Spencer Nadolsky.

We discuss:

• The origins of Ozempic and its predecessors
• How GLP-1 receptor drugs like Ozempic regulate appetite
• What the latest research and trials say about Ozempic’s effects (good and bad)
• Why we should quell the stigma borne from Ozempic’s brushes with celebrity culture
• Where studies on Ozempic and similar medications are going next
• How to ask your healthcare provider about Ozempic